1982-01-01
Fenmetrazin; 3-metyl-2-fenylmorfolin, Phenmetrazine; 3-methyl-2- kokain, Ecgonine, its esters and derivatives, which are convertible to ecgonine and cocaine.
Download the identifier in a file. IUPAC Standard InChIKey: QIQNNBXHAYSQRY-UHFFFAOYSA-N. CAS Registry Number: 7143-09-1. The two major urinary metabolites of cocaine are benzoylecgonine (BE) and ecgonine methyl ester (EME). The major advantage of BE screening is that many commercial immunoassays are designed to detect BE. On the other hand, EME is more amenable to gas chromatographic screening. To ascertain the merits … Recently, ecgonine methyl ester (methylecgonine) has been shown to be major urinary metabolite of cocaine in man after oral administration. These results indicate that ecgonine methyl ester is a prominent urinary metabolite after street use of cocaine, which primarily involves intranasal application and intravenous injection rather than ingestion.
Toxicol. 1988; 12: 301-306. 9. Weiss RD. Gawin, FH. Protracted elimination of cocaine metabolites in long-term, Letter to the editor i sensitive, selective, and rapid procedure for the quantitation of ecgonine methyl ester in urine to the editor: Transfer lower layer to a small Ecgonine Methyl.
Ecgonine (tropane derivative) is a tropane alkaloid found naturally in coca leaves. It has a close structural relation to cocaine: it is both a metabolite and a precursor, and as such, it is a controlled substance in many jurisdictions, as are some substances which can be used as precursors to ecgonine itself.
It is metabolized through deesterification to ecgonidine (ED or anhydroecgonine). When cocaine and alcohol are coabused there is a change in the metabolic pathway. Anhydroecgonine methyl ester (AEME) results from cocaine pyrolysis and can be used as a marker for crack cocaine use. Depending on the biological matrix examined, the amount of parent drug (cocaine) varies.
View the 3d structure. Other names: (-)-Ecgonine methyl ester; Methyl 3-hydroxy- 8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate;
Empirical Formula (Hill Notation) C 10 H 17 NO 3.
Weiss RD. Gawin, FH. Protracted elimination of cocaine metabolites in long-term,
Letter to the editor i sensitive, selective, and rapid procedure for the quantitation of ecgonine methyl ester in urine to the editor: Transfer lower layer to a small
Ecgonine Methyl. >10000. <0.5. Ester________________________________________________. Cross-Reactivity with Unrelated Drugs. According to stewards, "RASL reported that the urine sample was shown to contain benzoylecgonine and ecgonine methyl ester, which are
av G Höst · 2007 · Citerat av 5 — 5.1 Histidine based catalysis of ester hydrolysis in proteins…………… 33 cocaine, benzoylecgonine, and ecgonine methyl ester using electrospray ionization. Fenmetrazin, Phenmetrazine; 3-methyl-2-phenylmorpholine till ekgonin eller kokain, Ecgonine, its esters and derivatives, which are convertible to ecgonine and cocaine MPPP, MPPP; 1-methyl-4-phenyl-4-piperidinol proprionate (ester).
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Fenmetrazin, Phenmetrazine; 3-methyl-2-phenylmorpholine till ekgonin eller kokain, Ecgonine, its esters and derivatives, which are convertible to ecgonine and cocaine MPPP, MPPP; 1-methyl-4-phenyl-4-piperidinol proprionate (ester). Levophenacyl-morphan. → Ecgonine.
Binding and Dopamine Uptake.
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In this study, cocaine, benzoylecgonine, and ecgonine methyl ester excretion in urine was measured after intravenous and intranasal administration of cocaine
Molecular Formula C 10 H 17 NO 3; Average mass 199.247 Da; Monoisotopic mass 199.120850 Da; ChemSpider ID 94674 ECGONINE METHYL ESTER Y35FJB3QBJ Other Structure General Publications Names 5: Identifiers 5: Related Substances 5: ECGONINE METHYL ESTER Y35FJB3QBJ Other Details Stereochemistry: ABSOLUTE Molecular Formula: C10H17NO3: Molecular Weight CH$NAME: Ecgonine-methyl-ester (EME) CH$NAME: AC1L9FBF CH$NAME: methyl (3S,4R)-3-hydroxy-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate CH$COMPOUND_CLASS: N/A; Environmental Standard CH$FORMULA: C 10 H 17 NO 3 CH$EXACT_MASS: 199.1208434 CH$SMILES: COC(=O)[C@@H]1C2CCC(C[C@@H]1O)N2C ecgonine methyl ester ( CHEBI:31529 ) is a tropane alkaloid ( CHEBI:37332 ) ecgonine methyl ester ( CHEBI:31529 ) is conjugate base of ecgoninium methyl ester (1+) ( CHEBI:59908 ) Incoming. O -hydroxy (phenyl)phosphinoyl ecgonine methyl ester ( CHEBI:273574 ) has functional parent ecgonine methyl ester ( CHEBI:31529) ECGONINE METHYL ESTER HYDROCHLORIDE VY81V42YYZ Other Structure General Publications Names 6: Identifiers 2: Related Substances 3: ECGONINE METHYL ESTER … 129 mass spectra in 2 spectral trees are available online for the compound Ecgonine methyl ester . Last modification occurred on 2/25/2015 1:50:44 PM. mzCloud ‒ Free Online Mass Spectrometry Database Methyl ecgonine. Formula: C 10 H 17 NO 3. Molecular weight: 199.2469.
Many cocaine base (crack) exhibits contain traces of sodium bicarbonate. Pseudoecgonine methyl ester and ecgonine methyl ester are formed as artifacts from
Ecgonine phenylacetylmethyl ester. 2939.71. 1. Ethylmethylthiambutene (INN). 2934.99. 441-61-2. 319, 290511, Metanol (metylalkohol), Methanol (methyl alcohol) Propionsyra samt salter och estrar av propionsyra, Propionic acid, its salts and esters estrar och andra derivat av sådana ämnen, Cocaine, ecgonine, levometamfetamine, it replaced the normal methyl ester on the cocaine molecule with a plain to give benzoylecgonine (BE) and ecgonine methyl ester, and by (A) The esters of acid-function organic compounds of subchapters I to VII with organic compounds of these subchapters are to be classified with Chloromethane (Methyl chloride) and chloroethane Cocaine, ecgonine, levometamfetamine,.
Methylecgonidine is a pyrolysis product formed when crack cocaine is smoked, making this substance a useful biomarker to specifically test for use of crack cocaine, as opposed to powder cocaine which does not form methylecgonidine as a metabolite . [1] A method for the determination of cocaine (COC), benzoylecgonine (BE), ecgonine methyl ester (EME), and ecgonine (ECG) in plasma by liquid chromatography-mass spectrometry (LC-MS-MS) was developed. The analytes were isolated from human plasma by subsequent solid-phase extraction and were separated o …. ecgonine methyl ester. Definition: An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat.